{"id":31622,"date":"2021-07-19T05:00:00","date_gmt":"2021-07-19T03:00:00","guid":{"rendered":"https:\/\/www.mzone.cz\/?p=31622"},"modified":"2021-07-19T10:26:04","modified_gmt":"2021-07-19T08:26:04","slug":"cbd-ucinky-na-imunitni-system","status":"publish","type":"post","link":"https:\/\/www.mzone.cz\/en\/cbd-ucinky-na-imunitni-system\/","title":{"rendered":"Protiz\u00e1n\u011btliv\u00e9 konop\u00ed aneb \u00fa\u010dinky CBD na imunitn\u00ed syst\u00e9m"},"content":{"rendered":"

Ka\u017ed\u00fd den jsme vystaveni nep\u0159ebern\u00e9mu mno\u017estv\u00ed bakteri\u00ed, vir\u016f a dal\u0161\u00edm potenci\u00e1ln\u00edm neviditeln\u00fdm hrozb\u00e1m. V t\u011bchto p\u0159\u00edpadech se spol\u00e9h\u00e1me na imunitn\u00ed syst\u00e9m, d\u00edky n\u011bmu\u017e nedojde k po\u0161kozen\u00ed organismu, nicm\u00e9n\u011b pouze za p\u0159edpokladu, \u017ee funguje spr\u00e1vn\u011b. Imunitn\u00ed dysfunkce m\u016f\u017ee zp\u016fsobit autoimunitn\u00ed onemocn\u011bn\u00ed a celou \u0161k\u00e1lu zdravotn\u00edch probl\u00e9m\u016f, proto je t\u00e9m\u011b\u0159 \u017eivotn\u011b d\u016fle\u017eit\u00e9 udr\u017eovat spr\u00e1vnou \u010dinnost imunitn\u00edho syst\u00e9mu. V\u0161ichni v\u00edme, \u017ee je k tomu zapot\u0159eb\u00ed kvalitn\u00ed sp\u00e1nek, strava s dostate\u010dn\u00fdm obsahem \u017eivin a vitam\u00edn\u016f apod. St\u00e1le \u010dast\u011bji diskutovan\u00fdm prost\u0159edkem ke stabilizaci imunitn\u00edch funkc\u00ed je CBD (kanabidiol). Jak dok\u00e1\u017ee tento kanabinoid pomoci \u010dlov\u011bku br\u00e1nit se p\u0159ed eventu\u00e1ln\u00edmi hrozbami \u010d\u00edhaj\u00edc\u00edmi v\u0161ude kolem n\u00e1s?<\/strong><\/p>
\n\n\n\n

Jak funguje imunitn\u00ed syst\u00e9m?<\/h2>\n\n\n\n

Imunitn\u00ed syst\u00e9m (IS) je propracovan\u00e1 soustava bun\u011bk, tk\u00e1n\u00ed a jim nad\u0159azen\u00fdch org\u00e1n\u016f, kter\u00e9 dohromady zast\u00e1vaj\u00ed zejm\u00e9na funkci obrany organismu p\u0159ed p\u016fsoben\u00edm vir\u016f, bakteri\u00ed a dal\u0161\u00edch patogen\u016f. Krom\u011b toho tak\u00e9 mus\u00ed dok\u00e1zat odli\u0161it mrtvou \u010di jinak ne\u017e\u00e1douc\u00ed tk\u00e1\u0148 od zdrav\u00e9, kterou n\u00e1sledn\u011b vylou\u010d\u00ed z t\u011bla ven. Hlavn\u00ed \u00falohu zde hraj\u00ed 2 typy b\u00edl\u00fdch krvinek \u2013 lymfocyty a fagocyty. Zat\u00edmco fagocyty rozpozn\u00e1vaj\u00ed patogeny, je\u017e posl\u00e9ze odstra\u0148uj\u00ed, druh\u00fd typ b\u00edl\u00fdch krvinek slou\u017e\u00ed k zapamatov\u00e1n\u00ed hrozeb, aby mohl b\u00fdt imunitn\u00ed syst\u00e9m p\u0159\u00ed\u0161t\u011b dokonale p\u0159ipraven.<\/p>\n\n\n\n

Z\u00e1kladn\u00ed funkc\u00ed imunitn\u00edch bun\u011bk je tedy rozpozn\u00e1n\u00ed nep\u0159\u00edtele \u010di po\u0161kozen\u00e9 bu\u0148ky, tk\u00e1n\u011b atd. Dal\u0161\u00edm krokem je ozna\u010den\u00ed ne\u017e\u00e1douc\u00ed \u010d\u00e1sti, jej\u00ed odstran\u011bn\u00ed a zabr\u00e1n\u011bn\u00ed \u0161\u00ed\u0159en\u00ed. V neposledn\u00ed \u0159ad\u011b tak\u00e9 imunitn\u00ed bu\u0148ky zahajuj\u00ed proces hojen\u00ed, pokud ji\u017e do\u0161lo k po\u0161kozen\u00ed. <\/p><\/blockquote>\n\n\n\n

\"Imunita\"<\/figure>
\n\n\n\n

Souvislost mezi ECS a IS<\/h2>\n\n\n\n

Endokanabinoidn\u00ed syst\u00e9m (ECS) byl objeven pom\u011brn\u011b ned\u00e1vno, na po\u010d\u00e1tku 90. let 20. stolet\u00ed, p\u0159i\u010dem\u017e se okam\u017eit\u011b stal st\u0159edem z\u00e1jmu mnoha v\u011bdc\u016f. V\u0161ichni savci, v\u010detn\u011b \u010dlov\u011bka, disponuj\u00ed touto slo\u017eitou s\u00edt\u00ed kanabinoidn\u00edch receptor\u016f, enzym\u016f a p\u0159irozen\u00fdch endokanabinoidn\u00edch l\u00e1tek.<\/p>\n\n\n\n

ECS ovliv\u0148uje mnoho t\u011blesn\u00fdch i du\u0161evn\u00edch proces\u016f, nav\u00edc stabilizuje nervov\u00fd a imunitn\u00ed syst\u00e9m, tlum\u00ed bolest, zm\u00edr\u0148uje \u0161\u00ed\u0159en\u00ed z\u00e1n\u011btu, podporuje zdrav\u00fd sp\u00e1nek, reguluje chu\u0165 k j\u00eddlu atd.<\/p><\/blockquote>\n\n\n\n

\u201eLidsk\u00e9 t\u011blo si m\u016f\u017eeme p\u0159edstavit jako propracovan\u00fd stroj, p\u0159i\u010dem\u017e ECS a imunitn\u00ed syst\u00e9m jsou jeho podstatn\u00fdmi sou\u010d\u00e1stmi, kter\u00e9 se navz\u00e1jem ovliv\u0148uj\u00ed. D\u016fkazem toho je p\u0159\u00edtomnost kanabinoidn\u00edch receptor\u016f CB1 a CB2 p\u0159\u00edmo v IS \u2013 zejm\u00e9na potom CB2 receptor\u016f. Proto\u017ee se CBD (kanabidiol) v\u00e1\u017ee v\u00edce na receptory CB2, p\u0159irozen\u011b v\u00fdznamn\u00fdm zp\u016fsobem ovliv\u0148uje imunitn\u00ed funkce,\u201c popisuje Ji\u0159\u00ed Stabla, odborn\u00edk na konop\u00ed z Kanabigerol<\/a>.<\/p>
\n\n\n\n

Jak ovliv\u0148uje CBD imunitn\u00ed syst\u00e9m?<\/h2>\n\n\n\n

Drtiv\u00e1 v\u011bt\u0161ina studi\u00ed p\u0159i\u0161la s v\u00fdsledky, kter\u00e9 prok\u00e1zaly schopnost CBD zm\u00edr\u0148ovat z\u00e1n\u011bt neboli protiz\u00e1n\u011btliv\u00e9 vlastnosti. Co si pod t\u00edm ale p\u0159edstavit? Z\u00e1n\u011bt jako takov\u00fd je p\u0159irozenou reakc\u00ed organismu na po\u0161kozen\u00ed \u2013 jin\u00fdmi slovy, va\u0161e t\u011blo se vytv\u00e1\u0159en\u00edm z\u00e1n\u011btliv\u00fdch l\u00e1tek sna\u017e\u00ed vypo\u0159\u00e1dat se \u0161kodami. Velice \u010dasto b\u00fdv\u00e1 doprov\u00e1zen zv\u00fd\u0161enou teplotou, otokem, zarudnut\u00edm \u010di bolest\u00ed. Pom\u011brn\u011b b\u011b\u017enou a nikterak nebezpe\u010dnou variantou je tzv. akutn\u00ed z\u00e1n\u011bt, kter\u00fd odezn\u00ed v moment\u011b, kdy se tk\u00e1\u0148 zahoj\u00ed. O dost hor\u0161\u00ed je chronick\u00fd z\u00e1n\u011bt \u2013 ten p\u0159etrv\u00e1v\u00e1, a\u010dkoliv mnohdy v\u016fbec nen\u00ed z\u0159ejm\u00e9, \u017ee by posti\u017een\u00e9ho tr\u00e1pil n\u011bjak\u00fd zdravotn\u00ed probl\u00e9m. Jednou z p\u0159\u00ed\u010din chronick\u00e9ho z\u00e1n\u011btu m\u016f\u017ee b\u00fdt nespr\u00e1vn\u00e1 funkce imunitn\u00edho syst\u00e9mu, a to zejm\u00e9na p\u0159i hyperaktivn\u00ed reakci, p\u0159i kter\u00e9 IS \u00fato\u010d\u00ed na zdrav\u00e9 bu\u0148ky.<\/p>
\n\n\n\n

\"CBD<\/figure>
\n\n\n\n

Hloubkov\u00e1 studie<\/h2>\n\n\n\n

CBD potla\u010duje aktivitu imunitn\u00edho syst\u00e9mu, pokud nen\u00ed adekv\u00e1tn\u00ed vzhledem k ohro\u017een\u00ed, jemu\u017e je organismus vystaven. Tato jeho vlastnost je nejl\u00e9pe vyu\u017eiteln\u00e1 p\u0159i autoimunitn\u00edch onemocn\u011bn\u00edch, jako jsou psori\u00e1za (lup\u00e9nka), roztrou\u0161en\u00e1 skler\u00f3za, Crohnova nemoc \u010di revmatoidn\u00ed artritida.<\/p>\n\n\n\n

B\u0159ezen leto\u0161n\u00edho roku p\u0159inesl zaj\u00edmavou studii publikovanou v \u010dasopise Cannabis and Cannabinoid Research. Auto\u0159i se v n\u00ed zam\u011b\u0159ili na dosavadn\u00ed v\u00fdsledky v\u00fdzkum\u016f na t\u00e9ma \u201eImunitn\u00ed reakce regulovan\u00e9 kanabidiolem\u201c, z nich\u017e vypl\u00fdv\u00e1, \u017ee CBD je imunopresivn\u00ed l\u00e1tka \u2013 tj. disponuje schopnost\u00ed potla\u010dit z\u00e1n\u011bt.<\/p><\/blockquote>\n\n\n\n

Krom\u011b toho m\u00e1 v\u0161ak tak\u00e9 imunomodula\u010dn\u00ed \u00fa\u010dinky, d\u00edky kter\u00fdm m\u016f\u017ee v n\u011bkter\u00fdch p\u0159\u00edpadech napom\u00e1hat imunitn\u00ed reakci. Teoreticky by tak mohly z jeho vlastnost\u00ed t\u011b\u017eit ob\u011b skupiny, a sice lid\u00e9 s hyperaktivn\u00ed i nedostate\u010dnou imunitn\u00ed funkc\u00ed.<\/p>
\n\n\n\n

CBD na imunitu: Ano, nebo ne?<\/h2>\n\n\n\n

Odborn\u00edci i v\u011bde\u010dt\u00ed pracovn\u00edci nemaj\u00ed zcela jasno v tom, jak CBD p\u0159esn\u011b funguje p\u0159i modulaci imunitn\u00ed reakce organismu. Studie proveden\u00e9 na pacientech s autoimunitn\u00edm onemocn\u011bn\u00edm t\u00e9m\u011b\u0159 bezv\u00fdhradn\u011b dokazuj\u00ed pozitivn\u00ed \u00fa\u010dinky kanabidiolu, ale proto\u017ee jsou oba t\u011blesn\u00e9 syst\u00e9my \u2013 endokanabinoidn\u00ed i imunitn\u00ed \u2013 natolik slo\u017eit\u00fdm mechanismem, je pot\u0159eba m\u00edt se na pozoru. A to minim\u00e1ln\u011b do doby, ne\u017e bude cel\u00fd princip objasn\u011bn pomoc\u00ed klinick\u00fdch v\u00fdzkum\u016f.<\/p>
\n\n\n\n

\"CBD<\/figure>\n\n\n\n

\u201ePokud se \u010dlov\u011bk pot\u00fdk\u00e1 s nadm\u011brn\u00fdm v\u00fdskytem z\u00e1n\u011btu v t\u011ble, CBD by potenci\u00e1ln\u011b mohlo znamenat pomocn\u00e9 \u0159e\u0161en\u00ed, navzdory tomu je nezbytn\u00e9 v\u00e1\u0161 zdravotn\u00ed stav konzultovat s l\u00e9ka\u0159em,\u201c doporu\u010duje Ji\u0159\u00ed Stabla.<\/p><\/blockquote>\n\n\n\n

V z\u00e1v\u011bru studie si m\u016f\u017eeme p\u0159e\u010d\u00edst n\u00e1sleduj\u00edc\u00ed slova samotn\u00fdch autor\u016f, kter\u00e1 hovo\u0159\u00ed za v\u0161e: \u201eSt\u00e1le jsou zde ur\u010dit\u00e1 omezen\u00ed na\u0161ich znalost\u00ed o d\u00e1vkov\u00e1n\u00ed CBD, plazmatick\u00fdch hladin\u00e1ch a o tom, jak souvis\u00ed s imunitn\u00ed modulac\u00ed. N\u011bkter\u00e1 z t\u011bchto omezen\u00ed mohou b\u00fdt objasn\u011bna mnoha pl\u00e1novan\u00fdmi klinick\u00fdmi studiemi s CBD v nadch\u00e1zej\u00edc\u00edch letech.\u201c Tak si dr\u017eme palce!<\/p>
\n\n\n\n

\"Kratom\"<\/a><\/figure>
\n

V\u00edte, co je kratom? Pro n\u011bkoho droga, pro jin\u00e9 l\u00e9k<\/a><\/h4>
\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"

Ka\u017ed\u00fd den jsme vystaveni nep\u0159ebern\u00e9mu mno\u017estv\u00ed bakteri\u00ed, vir\u016f a dal\u0161\u00edm potenci\u00e1ln\u00edm neviditeln\u00fdm hrozb\u00e1m. V t\u011bchto p\u0159\u00edpadech se spol\u00e9h\u00e1me na imunitn\u00ed syst\u00e9m, d\u00edky n\u011bmu\u017e nedojde k po\u0161kozen\u00ed organismu, nicm\u00e9n\u011b pouze za p\u0159edpokladu, \u017ee funguje spr\u00e1vn\u011b. Imunitn\u00ed dysfunkce m\u016f\u017ee zp\u016fsobit autoimunitn\u00ed onemocn\u011bn\u00ed a celou \u0161k\u00e1lu zdravotn\u00edch probl\u00e9m\u016f, proto je t\u00e9m\u011b\u0159 \u017eivotn\u011b d\u016fle\u017eit\u00e9 udr\u017eovat spr\u00e1vnou \u010dinnost imunitn\u00edho syst\u00e9mu. […]<\/p>\n","protected":false},"author":4,"featured_media":31631,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"kk_blocks_editor_width":"","_kiokenblocks_attr":"","_kiokenblocks_dimensions":"","footnotes":""},"categories":[25,62],"tags":[4954,229,4213,4959,4965,2770,490,2967,1431,4137,4966,149],"class_list":["post-31622","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-style","category-zdravi","tag-cbd","tag-imunita","tag-imunitni-system","tag-kanabidiol","tag-kanabinoid","tag-konopi","tag-style","tag-ucinky","tag-vliv","tag-zanet","tag-zanety","tag-zdravi"],"yoast_head":"\nProtiz\u00e1n\u011btliv\u00e9 konop\u00ed aneb \u00fa\u010dinky CBD na imunitn\u00ed syst\u00e9m - Mzone<\/title>\n<meta name=\"description\" content=\"St\u00e1le \u010dast\u011bji diskutovan\u00fdm prost\u0159edkem ke stabilizaci imunitn\u00edch funkc\u00ed je CBD (kanabidiol). 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